San Francisco 49ers @ Cleveland Browns 10/15/23 Free Pick, NFL Odds, NFL Predictions

San Francisco 49ers (5-0) at Cleveland Browns (2-2)

Game Info: Sunday, October 15th, 2023 at  1:00 p.m. EST (Cleveland Browns Stadium)

Betting Odds: San Francisco 49ers -9.5 (-110) - Over/Under (36)

Pick: San Francisco 49ers -9.5 (-110)

The San Francisco 49ers will come into Cleveland looking to remain undefeated on the season after already picking up one victory on the road against an AFC North team. Cleveland is coming off of a week and they will be looking to grab a victory against one of the best teams in the league even without starting quarterback Deshaun Watson who will be missing his second consecutive game thanks to some tightness and bruising in his shoulder. Both of these teams will be looking for a crucial win as we get closer and closer to the midway point of the regular season.

It has been a fantastic start to the season for the San Francisco 49ers. They have easily looked like the best team in the entire league as they have rattled off five consecutive victories to open up the year, and it looks like that will keep happening throughout the remainder of the season with the way they have been playing so far this year. Running back Christian McCaffrey has looked absolutely unstoppable at times and if he doesn’t hurt you, it is the other four or five offensive weapons, this team possesses like tight end, George Kittle, and wide receivers Brandon Ayiuk, and Deebo Samuel. 

This is a San Francisco 49ers team that looks like the favorites at the moment to win the NFC and potentially even the Super Bowl despite the success of both the Kansas City Chiefs and the Philadelphia Eagles throughout the first five weeks of the season as well. San Francisco will be looking to pick up their second victory over an AFC North team on the road after they opened up the season with a victory over the Pittsburgh Steelers in Pittsburgh only five weeks ago.

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The Cleveland Browns come into this game with two victories to their name on the season, but they also have a pair of losses on their record as well. Both of those losses can be disputed as they likely should’ve won the Pittsburgh Steelers game back in week two on Monday night. However, two weeks ago against the Baltimore Ravens Cleveland looked absolutely lost as they did not have starting quarterback to Deshaun Watson, and they will not have him in this game either as he will miss his second consecutive game of the season after having the last two weeks to recover with the bye week coming last week for the Cleveland Browns. 

It will be a tough hill to climb for Cleveland, and after the performance of rookie quarterback, Dorian Thompson Robinson during the Baltimore Ravens game, NFL, veteran PJ Walker will get the start for the Cleveland Browns here on Sunday afternoon at home as they believe he gives them a better chance to be competitive in this game. This is a team that has a very solid defense that could easily keep them in this football game but they will have a lot of work ahead of them if they want to get a victory over the San Francisco 49ers here on Sunday afternoon at home to pick up their third win of the year.

Betting trends to consider in this matchup:

- San Francisco is 4-1 against the spread 

- The 49ers are 1-0 against the spread against the AFC

- Cleveland is 0-1 against the spread as an underdog 

I expect this to be all San Francisco here on Sunday afternoon in Cleveland as I look for the 49ers to grab a comfortable victory over a struggling Cleveland Browns team that will be without their starting quarterback for the second game in a row. I look for this to be a close and competitive game throughout the early stages of the contest, but in the end, I have the San Francisco 49ers, pulling away to grab the victory over the Cleveland Browns here in week number six of the season.

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